1. Tom and Jerry
   Dewey and Louie
2. Muttley and Jeff
   Mighty and Mickey Mouse

In their first episodes, Tom was actually named Jasper, while Jerry was referred to as Jinx. For years, Tom and Jerry were long-term enemies and became friends only in 1975.

1. Foghorn Leghorn
   Speedy Gonzales
2. Pluto
   Popeye

This cartoon is based on the titular comic strip about Popeye the Sailor that first appeared in 1929. Over the years, Popeye has also appeared in comic books, television cartoons, arcade and video games, hundreds of advertisements (he advertised everything from vegetables to candy cigarettes), and the 1980 live-action film starring Robin Williams as Popeye.

1. Pink Panther
   Wonder Woman
2. Bobby Hill
   Boris Badenov

Originally a movie series featured a French detective, Jacques Clouseau. The “Pink Panther” was not an animal there but a diamond that had a flaw in the center and resembled a panther. The movie credits featured an actual cartoon panther that was pink, and this evolved into a cartoon show starring a pink panther.

1. Mickey Mouse
   Shaggy
2. Bugs Bunny
   Popeye

The cute mouse Mickey is, by far, the Walt Disney Company's most famous and recognizable character. Moreover, he is considered to be the most popular cartoon character in the whole world.

1. Bullwinkle
   Daffy Duck
2. Bugs Bunny
   Porky Pig

Cool, smart and confident, Bugs Bunny is always a few steps ahead of everybody else. The main protagonist of The Looney Tunes Show franchise lives in an upper-middle-class suburban neighborhood, spending money he earned from inventing the carrot peeler.

1. Winnie the Pooh
   Lucy van Pelt
2. Underdog
   Captain Caveman

Did you know that the real life bear, Winnie, from the London Zoo, started it all? However, unlike in the books or cartoons, Winnie was originally a girl. And while it's true that the storybook character was inspired by a stuffed bear the writer's son owned, the plush toy was named after this Canadian bear his son saw at the London Zoo. The "Pooh" part of Winnie's name actually came from a swan the Milne family saw on vacation.

1. Mr. Magoo
   Scooby-Doo
2. Mickey Mouse
   Spider-Man

The life of this nerdy, shy and awkward high school student changed forever after he was bitten by a genetically modified spider. After he gained spider-like abilities, he decided to use them to protect his city, since with great power comes great responsibility.

1. Homer Simpson
   Gumby
2. Underdog
   Tweety Bird

Overweight, lazy and selfish, Homer Simpson is still one of the best characters of the American animated television series, "The Simpsons." Despite all his flaws and his obviously below average intelligence, he has shown moments of great intellect. Homer can be also a caring parent and husband (sometimes).

1. Sylvester
   Superman
2. Porky Pig
   Winnie the Pooh

This most powerful superhero is easily recognized across the globe. Since Superman's debut in 1938, he’s starred in at least one regular monthly comic, numerous cartoons, blockbuster films and television shows.

1. Angelica Pickles
   George of the Jungle
2. Superman
   Batman

Batman is proof that you don’t need superpowers to be a real superhero who will make the world a better place. The Dark Knight of Gotham City begins his war on crime with his first big enemy - the clownishly homicidal Joker.

1. Fred Flintstone
   Henery Hawk
2. Boo-Boo Bear
   Atom Ant

Aired 30 years before "The Simpsons," "The Flintstones was the first prime-time animated show on TV. It's the story of Fred and Wilma Flintstone and their neighbors who live in Bedrock in 10,000 B.C. Originally, the show was called "The Gladstones," then the creators decided on "The Flagstones," until they realized there was a comic strip with the same name.

1. Yogi Bear
   Betty Boop
2. Mr. Magoo
   Fred Flintstone

Yogi Bear made his debut in "The Huckleberry Hound Show" in 1958. Since then, he has appeared in numerous comic books, animated television shows and films. Ever wondered why he had a collar? This allowed animators to keep his body static, redrawing only his head when he spoke, This simple method reduced the number of drawings needed for a seven-minute cartoon drastically - from around 14,000 to around 2,000.

1. Charlie Brown
   Hugo the Abominable Snowman
2. Chip
   George Jetson

A nuclear family, the Jetsons — George, Jane, Judy, Elroy, Astro the dog and Rosie the robot maid — lived in Orbit City in the year 2062. (Even though it's not stated on the show, this date appeared in some press materials.)

1. Scrooge McDuck
   Fred Flintstone
2. Wile E. Coyote
   SpongeBob SquarePants

Scrooge McDuck first appeared in a Donald Duck comic in 1947. Originally, it was supposed to be his only appearance, but the rich duck became so popular he appeared in a number of cartoons, shows and comics. In 2012, The Billfold website tried to figure out how rich Scrooge is: they used the average height of a duck in order to calculate how much money is in his money vault and came up with the rough estimate of $31.2 billion!

1. Peter Griffin
   Donald Duck
2. Tweety Bird
   Alvin

Peter Griffin was born on July 22, 1955, in Mexico. This typical American guy is of Irish descent and lives in Quahog, Rhode Island, with his wife, Lois, and their three children, Meg, Chris and Stewie. He also has a dog named Brian, who is his best friend.

1. Charlie Brown
   Arthur
2. Popeye
   Space Ghost

According to his creator, Charles M. Schulz, Charlie is a caricature of the average person. He became one of the best-known cartoon characters of all time and one of the great American archetypes.

1. Stitch
   Pinky
2. Wile E. Coyote
   Huckleberry Hound

Wile E. Coyote, genius. That’s how he introduce himself, and, honestly, he deserves the credit! He is great at creating elaborating schemes and plans in order to get a meal. And, after all, does it matter that all of his schemes failed?

1. The Peanuts gang
   The Grinches
2. The Powerpuff Girls
   Josie and the Pussycats

Three super-powered little girls, Blossom, Bubbles and Buttercup, were accidentally created in a lab by Professor Utonium. They constantly save their town, Townsville, from monsters. What are they made of? Sugar, spice and everything nice!

1. Pink Panther
   SpongeBob SquarePants
2. Bart Simpson
   Bobby Hill

Voiced by Pamela Adlon, Robert Jeffrey "Bobby" Hill is the best character on the animated series "King of the Hill" - he's insightful, funny, always keeps it real and is never afraid to speak his mind.

1. Mighty Mouse
   Archer
2. Mr. Magoo
   Yogi Bear

Savvy, brave, and sophisticated spy Archer has the coolest gadgets and has saved the world multiple times. But when it comes to dealing with his boss, who is also his mother, he is not that cool anymore.

1. Speed Racer and friends
   Phineas and Ferb
2. The Grinches
   The Flintstones

Phineas Flynn and his stepbrother, Ferb Fletcher, know how to make every day of their summer vacation fun. They tried everything from building a huge roller coaster to traveling back in time and meeting dinosaurs. No matter what they do, they enjoy every minute of it!

1. Beavis
   Ben Tennyson
2. Betty Boop
   George Jetson

Benjamin "Ben" Kirby Tennyson, the protagonist of the Cartoon Network series, "Ben 10," was an ordinary ten-year-old kid until he received an Omnitrix. This powerful watch-like device allows him to turn into a variety of different aliens!

1. Mickey and Minnie
   Beavis and Butt-Head
2. Tom and Jerry
   Magica De Spell

"Beavis and Butt-Head" original episodes, books , movie and soundtrack were enjoyed by millions, from its debut on March 8, 1993 until its original end in 1997, and again during its brief return in 2011. It was one of the most controversial and bravest shows on national TV.

1. Philip J. Fry
   Bugs Bunny
2. Homer Simpson
   Mickey Mouse

Meet the main character of the animated sitcom, "Futurama"! Philip J. Fry is a popular cartoon character, but nobody really knows his age. All we know is that Fry was frozen at age 25 for 1,000 years making him 1025, then youthisized to age 14, reverse-aged to near unbirth, then re-aged, supposedly to his correct biological age, 29. But then he went back in time and was frozen again... maybe you can figure out how old is he now?

1. Homer Simpson
   The Grinch
2. Snagglepuss
   Penelope Pitstop

This beautiful cartoon is based on the iconic children's tale by Dr. Seuss, "How the Grinch Stole Christmas!" (1957). Notably, Tim Burton was almost the director of the live-action version, but since had a conflict with another movie, Ron Howard directed it.

1. Jiminy Cricket
   Wally Gator
2. Donald Duck
   Magilla Gorilla

Donald Duck was born in Walt Disney's cartoon, "The Wise Little Hen," in 1934. The character was created when Walt Disney heard Clarence Nash having fun and doing his "duck" voice while reciting "Mary Had a Little Lamb."

1. Daria
   Batman
2. Bart Simpson
   George Jetson

Bart Simpson was born on April 1, 1979, and - according to a "Treehouse of Horror" episode - has a formerly conjoined twin brother named Hugo. Bart Simpson’s character is loosely based on comic book character Dennis the Menace.

1. Shaggy
   Eeyore
2. Scrooge McDuck
   Spike Bulldog

Shaggy is the best friend and owner of Scooby-Doo. They are a great match - both are cowardly slackers who are more interested in eating than in solving mysteries. Interestingly, these two are the only characters to appear in all iterations of the franchise.

1. Josie
   Jeckle
2. Tweety Bird
   Angelica Pickles

Angelica is honestly one of the best characters in the popular animated TV series, "Rugrats." She is selfish and spoiled, but also truly adorable! In 2002, TV Guide placed Angelica Pickles 7th in their popular list of Top 50 Greatest Cartoon Characters of All Time.

1. Barney Rubble
   Penelope Pussycat
2. Porky Pig
   Dopey

Porky Pig is widely known for his signature line at the end of each short - "Th-Th-Th-That's All Folks!" The original voice of Porky Pig, voice actor Joe Dougherty, also had a stutter.

1. Scooby-Doo
   Thumper
2. Woody Woodpecker
   Hong Kong Phooey

Great Dane dog named Scooby-Doo (full name Scoobert Doo), his loyal human friend Shaggy, and three of their teen friends have been on TV since 1969. The first series, "Scooby-Doo, Where Are You!, aired Saturday mornings on CBS and lasted 25 episodes.

1. The Chipmunks
   The Peanuts kids
2. Duey, Dewey and Louie
   Three Blind Mice

Meet the unforgettable trio of singing chipmunks: mischievous leader Alvin, smart Simon, and chubby, funny Theodore. In the 2007 movie, when they find their tree cut down and go to Los Angeles, they meet the frustrated songwriter David Seville (Jason Lee), who is deeply impressed by their singing talent.

1. Quick Draw McGraw
   Arthur
2. Bambi
   Velma Dinkley

Cool aardvark Arthur Read teaches kids how to deal with a lot of childhood challenges including homework, teachers and bullies. Based on the books by Marc Brown, this cute cartoon features an 8-year-old aardvark, his family and friends as they grow up and learn how to be good to each other.

1. The Grinch
   Snoopy
2. Stitch
   Pink Panther

An illegally-made, genetically-engineered creature that looks like a blue koala, Stitch was designed to be mischievous and dangerous. Even though he became Lilo's best friend, he is still unlikable to many people because of his weird and temperamental behavior.

1. Yogi Bear
   Jimmy Neutron
2. Elmer Fudd
   Tigger

"Jimmy Neutron" was one Nickelodeon hit shows that also won an Annie Award for Outstanding Achievement in an Animated Television Production Produced For Children in 2004.

1. Speed Buggy
   Samurai Jack
2. Jonny Quest
   Goofy

A young samurai named Jack was sent into the future by evil wizard Aku. Now, he tries his best to return to the past and undo the wizard's spell.

1. Shaggy Rogers
   Stan Smith
2. Tweety
   Winnie-the-Pooh

Stan is the main character of the adult animated sitcom, "American Dad!" He works for the CIA and usually applies the same extreme measures used for his job in his personal life and when dealing with family problems.

1. Top Cat
   Stimpy
2. Patrick Star
   Piglet

Patrick lives under a rock and is SpongeBob's best friend. This adorable fat pink starfish can be stupid, but he is also (rarely) capable of random bursts of intelligence.

1. Pepé Le Pew
   Yosemite Sam
2. SpongeBob SquarePants
   Tinker Bell

According to his driver’s license, shown in one of the episodes, SpongeBob SquarePants was born July 14, 1986! So, as for now, he is in his 30s already. Whoa!

1. Daffy Duck
   Jerry
2. Droopy
   Charlie Brown

Duffy Duck first appeared in 1937 in the short, "Porky's Duck Hunt." In his early days he was a hyperactive, at times silly duck, whose frequent sidekick was Porky Pig.

1. Larry the Cucumber and Carrot
   Rocky and Bullwinkle
2. Bart and Lisa
   Pebbles and Bam-Bam

"Rocky and His Friends" is a funny cartoon that primary features the adventures of a heroic flying squirrel and his stupid but adorable moose friend.

1. The Road Runner and Wile E. Coyote
   Pinky and the Brain
2. Marvin the Martian
   Scooby-Doo

Pinky and the Brain first starred in a recurring one-act segment on the classic Animaniacs. Two weird buddies became so popular after, that they were quickly promoted and got their own TV series in 1995.

1. Daphne Blake
   Stewie Griffin
2. Penelope Pitstop
   Phineas Flynn

Daphne comes from a wealthy family and is famous for her red hair, lavender heels, fashion sense and a knack for getting into danger. She is also known by her nickname, "Danger Prone Daphne."

1. Gumball
   Jessica Rabbit
2. Tasmanian Devil
   Bullwinkle

Young, hyperactive, and with a flair for misadventure, the cat named Gumball Watterson is the main character in the animated TV series, "The Amazing World of Gumball."

1. Mighty Mouse
   Fat Albert
2. Lisa Simpson
   Timmy Turner

Neglected by his parents and abused by his evil babysitter Vicky, Timmy has a hard life, but his fairy godparents, Cosmo and Wanda, always try to make things a little bit easier for him.

1. Bender
   Goofy
2. Stewie Griffin
   The Tick

Obsessed with violence, little Stewie is just one year old and doesn't have an official birthday. The baby has a unique head shape, which none of his family members share, and he is voiced by Family Guy creator Seth MacFarlane.

1. Yogi and Boo-Boo
   Tom and Jerry
2. Ren and Stimpy
   Itchy and Scratchy

Ren the chihuahua and Stimpson J. Cat, who goes by the nickname Stimpy, had a lot of unusual adventures back in the 90s. By the way, Stimpy, who certainly doesn't look like a cat in the real world, was inspired by a Tweety Bird cartoon.

1. Eric Cartman
   Mickey Mouse
2. Heckle
   Droopy

"South Park" has been on the air since 1997, still cranking out new episodes, which comes as a bit of a surprise for people who stopped watching it like 10 years ago. Yes, "South Park" is still going strong, but it's not the same anymore.

1. Jerry
   Felix
2. Fred Jones
   Woody Woodpecker

A tall, muscular, blond teenager with a massive chin, Fred Jones is a new leader of Crystal Cove's newest incarnation of Mystery Incorporated. Over the years, Fred built a lot of overly complicated traps for villains, which Scooby-Doo, along with Shaggy, would often set off by mistake.

1. Donald Duck
   Wile E. Coyote
2. Tom
   Dora the Explorer

The inspiration for the name Dora Marquez was exploradora, the Spanish feminine word for explorer, and the last name of the acclaimed writer Gabriel García Márquez.